Whole Genome Sequencing
Whole genome sequencing is the determination of the entire DNA sequence of an organism. This provides an unparalleled view of the genetic composition of the organism being studied.
By sequencing the entire genome, we can analyse larger structural differences between different samples. Occurrences such as translocations are difficult to identify by targeted methods, as the complete regions of interest are often not covered.
Whole genome sequencing also allows for the analysis of genetic differences such as Single Nucleotide Polymorphisms (SNPs) and Copy Number Variation (CNV) within large non-coding regions of the genome. These differences provide an insight into the genetic lineage of an organism, and thus are incredibly valuable to the investigation of evolution.
It is possible to sequence novel organisms and assemble the sequencing data by a de novo assembly, to provide an accurate DNA sequence for a previously unknown organism.
Whole genome sequencing is possible for both large and small genomes, and our technical sales team are able to provide advice on the most suitable library preparation and sequencing platform for your sequencing project.
For further information and prices please contact us or call +44 (0)115 973 9012